MIT Open Access Articles: Recent submissions

Now showing items 220-222 of 55604

    • Stereoselective Synthesis of Trisubstituted Alkenes via Copper Hydride-Catalyzed Alkyne Hydroalkylation 

      Kutateladze, Dennis A; Mai, Binh Khanh; Dong, Yuyang; Zhang, Yu; Liu, Peng; e.a. (American Chemical Society, 2023-08-04)
      Alkenes are ubiquitous in organic chemistry, yet many classes of alkenes remain challenging to access by current synthetic methodology. Herein, we report a copper hydride-catalyzed approach for the synthesis of Z-configured ...

    • Room‐Temperature Copper‐Catalyzed Etherification of Aryl Bromides 

      Strauss, Michael J; Greaves, Megan E; Kim, Seoung‐Tae; Teijaro, Christiana N; Schmidt, Michael A; e.a. (Wiley, 2024-02-15)
      We disclose the development of a Cu-catalyzed C−O coupling method utilizing a new N1,N2-diarylbenzene-1,2-diamine ligand, L8. Under optimized reaction conditions, structurally diverse aryl and heteroaryl bromides underwent ...

    • CuH-Catalyzed Regio- and Enantioselective Formal Hydroformylation of Vinyl Arenes 

      Garhwal, Subhash; Dong, Yuyang; Mai, Binh Khanh; Liu, Peng; Buchwald, Stephen L (American Chemical Society, 2024-05-09)
      A highly enantioselective formal hydroformylation of vinyl arenes enabled by copper hydride (CuH) catalysis is reported. Key to the success of the method was the use of the mild Lewis acid zinc triflate to promote the ...