MIT Open Access Articles: Recent submissions
Now showing items 1-3 of 53881
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Targeting and monitoring ovarian cancer invasion with an RNAi and peptide delivery system
(Proceedings of the National Academy of Sciences, 2024-03-04)RNA interference (RNAi) therapeutics are an emerging class of medicines that selectively target mRNA transcripts to silence protein production and combat disease. Despite the recent progress, a generalizable approach for ... -
Carboxylated Nanoparticle Surfaces Enhance Association with Mucoid Pseudomonas aeruginosa Biofilms
(American Chemical Society, 2024-03-14)Pseudomonas aeruginosa biofilms comprise three main polysaccharides: alginate, psl, and pel, which all imbue tolerance against exogenous antimicrobials. Nanoparticles (NPs) are an exciting new strategy to overcome the ... -
Poly(β-aminoester) Physicochemical Properties Govern the Delivery of siRNA from Electrostatically Assembled Coatings
(American Chemical Society, 2024-04-30)Localized short interfering RNA (siRNA) therapy has the potential to drive high-specificity molecular-level treatment of a variety of disease states. Unfortunately, effective siRNA therapy suffers from several barriers to ...
