MIT Open Access Articles: Recent submissions

Now showing items 1-3 of 55385

    • Room‐Temperature Copper‐Catalyzed Etherification of Aryl Bromides 

      Strauss, Michael J; Greaves, Megan E; Kim, Seoung‐Tae; Teijaro, Christiana N; Schmidt, Michael A; e.a. (Wiley, 2024-02-15)
      We disclose the development of a Cu-catalyzed C−O coupling method utilizing a new N1,N2-diarylbenzene-1,2-diamine ligand, L8. Under optimized reaction conditions, structurally diverse aryl and heteroaryl bromides underwent ...

    • CuH-Catalyzed Regio- and Enantioselective Formal Hydroformylation of Vinyl Arenes 

      Garhwal, Subhash; Dong, Yuyang; Mai, Binh Khanh; Liu, Peng; Buchwald, Stephen L (American Chemical Society, 2024-05-09)
      A highly enantioselective formal hydroformylation of vinyl arenes enabled by copper hydride (CuH) catalysis is reported. Key to the success of the method was the use of the mild Lewis acid zinc triflate to promote the ...

    • Cu-Catalyzed Amination of Base-Sensitive Aryl Bromides and the Chemoselective N- and O-Arylation of Amino Alcohols 

      Strauss, Michael J; Liu, Kaylee X; Greaves, Megan E; Dahl, Jakob C; Kim, Seoung-Tae; e.a. (American Chemical Society, 2024-06-26)
      We report a general and functional-group-tolerant method for the Cu-catalyzed amination of base-sensitive aryl bromides including substrates possessing acidic functional groups and small five-membered heteroarenes. The ...