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Now showing items 15761-15770 of 15788
Scalable Chemical Tool for Analyzing Brain: Electron Microscope-Like Images with Fluorescent Microscope
(Massachusetts Institute of Technology, 2023-06)
Neuroscientists have long studied complex neural circuits by examining their ultrastructure and molecular features. Electron microscopy (EM) has greatly advanced our fundamental understanding of neurobiology by revealing ...
Design of an Affordable, Precise Irrigation Controller that Lowers the Barrier to Water- and Energy-Sustainable Agriculture
(Massachusetts Institute of Technology, 2024-02)
With climate change and population growth exacerbating global food insecurity, it has become urgent to establish more water- and energy-efficient means to raise agricultural production. Available techniques to bolster crop ...
Targeting and Manipulating Endogenous Transcriptional Condensates
(Massachusetts Institute of Technology, 2023-02)
Biomolecular condensates are membraneless compartments composed of selectively concentrated biomolecules with liquid-like properties. In this thesis, we discuss our discoveries showing that biomolecular condensates are ...
Temporal gene expression and regulation in T4 phage
(Massachusetts Institute of Technology, 2024-02)
As the most abundant biological entity in the biosphere, bacteriophages play a critical role in shaping the microbial diversity, and thus overall ecosystem health. They are also essential tools in molecular biology, shedding ...
Interplay between Extra-Germinal Center expansion of memory B cells and affinity maturation during the humoral recall response
(Massachusetts Institute of Technology, 2023-09)
According to the WHO, vaccines have saved more lives than any other medical intervention in history. Current estimates suggest vaccines save millions of lives annually. The importance of vaccines was recently highlighted ...
Messy Measurement: Approaches to Causal Inference With Unobserved Variables
(Massachusetts Institute of Technology, 2023-09)
This dissertation focuses on methods for conducting causal inference when an essential variable is unobserved. The first paper provides new methods for causal inference with bundled variables. A bundled variable is one ...
Empowering Users on Social Media for Better Content Credibility
(Massachusetts Institute of Technology, 2023-09)
As misinformation raged on online social spaces and threatened people’s lives and even democracy, platforms rose as the authority on misinformation detection and moderation. However, concerns about freedom of speech and ...
High Entropy Amorphous and Crystalline Li-Garnet Films for Lithionic Applications
(Massachusetts Institute of Technology, 2023-06)
Safe, reliable, and Li+-conductive solid-state electrolytes are considered the key to unlocking the potential of solid-state and hybrid batteries, as well as lithionic devices beyond batteries, such as memristors and ...
Methods to program and to probe RNA tertiary structure with nucleic acid origami
(Massachusetts Institute of Technology, 2022-05)
Biological structure determination has revolutionized mechanistic understandings, nanotechnology, and drug design. Despite advances in structural determination technologies, from nuclear magnetic resonance to cryo-electron ...
Diversity and Expertise in Representative Governance
(Massachusetts Institute of Technology, 2023-09)
Representative democracy is a widespread and essential part of democratic governance. Our understanding of it has been largely shaped by the triumph of elections that vest peripheral access to power through episodical ...