Browsing MIT Open Access Articles by Title

Now showing items 43380-43399 of 55821

    • s- process enrichment of ultrafaint dwarf galaxies 

      Tarumi, Yuta; Suda, Takuma; van de Voort, Freeke; Inoue, Shigeki; Yoshida, Naoki; e.a. (Oxford University Press (OUP), 2021)
      <jats:title>ABSTRACT</jats:title> <jats:p>We study the production of barium (Ba) and strontium (Sr) in ultrafaint dwarf (UFDs) galaxies. Both r- and s- processes produce these elements, and one can infer ...

    • S-nitrosation of proteins relevant to Alzheimer's disease during early stages of neurodegeneration 

      Bhat, Vadiraja B.; Seneviratnea, Uthpala; Nott, Alexi; Ravindra, Kodihalli C.; Wishnok, John S; e.a. (National Academy of Sciences (U.S.), 2016-03)
      Protein S-nitrosation (SNO-protein), the nitric oxide-mediated posttranslational modification of cysteine thiols, is an important regulatory mechanism of protein function in both physiological and pathological pathways. A ...

    • S-nitrosation of proteins relevant to Alzheimer’s disease during early stages of neurodegeneration 

      Bhat, Vadiraja B.; Seneviratne, Uthpala Indrajith; Nott, Alexander; Kodihalli, Ravindra; Wishnok, John S; e.a. (National Academy of Sciences (U.S.), 2016-04)
      Protein S-nitrosation (SNO-protein), the nitric oxide-mediated posttranslational modification of cysteine thiols, is an important regulatory mechanism of protein function in both physiological and pathological pathways. A ...

    • S-nitrosylation of E3 ubiquitin-protein ligase RNF213 alters non-canonical Wnt/Ca+2 signaling in the P301S mouse model of tauopathy 

      Amal, Haitham; Gong, Guanyu; Gjoneska, Elizabeta; Lewis, Sarah M; Wishnok, John S.; e.a. (Springer Nature, 2019-01)
      Mutations in the MAPT gene, which encodes the tau protein, are associated with several neurodegenerative diseases, including frontotemporal dementia (FTD), dementia with epilepsy, and other types of dementia. The missense ...

    • S-Nitrosylation of PINK1 Attenuates PINK1/Parkin-Dependent Mitophagy in hiPSC-Based Parkinson’s Disease Models 

      Oh, Chang-Ki; Sultan, Abdullah; Platzer, Joseph; Dolatabadi, Nima; Soldner, Frank; e.a. (Elsevier, 2017-11)
      Mutations in PARK6 (PINK1) and PARK2 (Parkin) are linked to rare familial cases of Parkinson's disease (PD). Mutations in these genes result in pathological dysregulation of mitophagy, contributing to neurodegeneration. ...

    • S-Store: a streaming NewSQL system for big velocity applications 

      Cetintemel, Ugur; Tufte, Kristin; Wang, Hao; Zdonik, Stanley; Du, Jiang; e.a. (Association for Computing Machinery (ACM), 2014-08)
      First-generation streaming systems did not pay much attention to state management via ACID transactions (e.g., [3, 4]). S-Store is a data management system that combines OLTP transactions with stream processing. To create ...

    • S-Store: streaming meets transaction processing 

      Meehan, John; Pavlo, Andrew; Tufte, Kristin; Zdonik, Stan; Aslantas, Cansu; e.a. (Association for Computing Machinery, 2015-09)
      Stream processing addresses the needs of real-time applications. Transaction processing addresses the coordination and safety of short atomic computations. Heretofore, these two modes of operation existed in separate, ...

    • S100A9-RAGE Axis Accelerates Formation of Macrophage-Mediated Extracellular Vesicle Microcalcification in Diabetes Mellitus 

      Kawakami, Ryo; Katsuki, Shunsuke; Travers, Richard; Romero, Dayanna Carolina; Becker-Greene, Dakota; e.a. (Ovid Technologies (Wolters Kluwer Health), 2020)
      © 2020 American Heart Association, Inc. Objective: Vascular calcification is a cardiovascular risk factor and accelerated in diabetes mellitus. Previous work has established a role for calcification-prone extracellular ...

    • S2ADC: A 12-bit, 1.25MS/s Secure SAR ADC with Power Side-Channel Attack Resistance 

      Jeong, Taehoon; Chandrakasan, Anantha P; Lee, Hae-Seung (Institute of Electrical and Electronics Engineers (IEEE), 2020-04)
      This paper presents a neural-network-based SAR ADC power side-channel attack (PSA) method and a 12-bit, 1.25MS/s secure SAR ADC whose current equalizers protect the ADC from PSA. A prototype SAR ADC was fabricated in 65nm ...

    • S[subscript n]-equivariant sheaves and Koszul cohomology 

      Yang, David H. (Springer, 2014-11)
      Purpose: We give a new interpretation of Koszul cohomology, which is equivalent under the Bridgeland-King-Reid equivalence to Voisin's Hilbert scheme interpretation in dimensions 1 and 2 but is different in higher ...

    • Sacred Cars? Cost-Effective Regulation of Stationary and Nonstationary Pollution Sources 

      Fowlie, Meredith; Knittel, Christopher Roland; Wolfram, Catherine (American Economic Association, 2012-02)
      For political and practical reasons, environmental regulations sometimes treat point-source polluters, such as power plants, differently from mobile-source polluters, such as vehicles. This paper measures the extent of ...

    • Sacrificial-Post Templating Method for Block Copolymer Self-Assembly 

      Alexander-Katz, Alfredo; Ross, Caroline A.; Berggren, Karl K.; Tavakkoli Kermani Ghariehali, Amir; Nicaise, Sam; e.a. (Wiley Blackwell, 2013-07)
      A sacrificial-post templating method is presented for directing block copolymer self-assembly to form nanostructures consisting of monolayers and bilayers of microdomains. In this approach, the topographical post template ...

    • Saddle Point in the Minimax Converse for Channel Coding 

      Polyanskiy, Yury (Institute of Electrical and Electronics Engineers, 2013-05)
      A minimax metaconverse has recently been proposed as a simultaneous generalization of a number of classical results and a tool for the nonasymptotic analysis. In this paper, it is shown that the order of optimizing the ...

    • Saddle point localization of molecular wavefunctions 

      Mellau, Georg Ch.; Kyuberis, Alexandra A.; Polyansky, Oleg L.; Zobov, Nikolai; Field, Robert W (Nature Publishing Group, 2016-09)
      The quantum mechanical description of isomerization is based on bound eigenstates of the molecular potential energy surface. For the near-minimum regions there is a textbook-based relationship between the potential and ...

    • Safe and Effective In Vivo Targeting and Gene Editing in Hematopoietic Stem Cells: Strategies for Accelerating Development 

      Cannon, Paula; Asokan, Aravind; Czechowicz, Agnieszka; Hammond, Paula; Kohn, Donald B; e.a. (Mary Ann Liebert Inc, 2021)
      On May 11, 2020, the National Institutes of Health (NIH) and the Bill & Melinda Gates Foundation (Gates Foundation) held an exploratory expert scientific roundtable to inform an NIH-Gates Foundation collaboration on the ...

    • Safe and Effective In Vivo Targeting and Gene Editing in Hematopoietic Stem Cells: Strategies for Accelerating Development 

      Cannon, Paula; Asokan, Aravind; Czechowicz, Agnieszka; Hammond, Paula; Kohn, Donald B; e.a. (Mary Ann Liebert Inc, 2021-01)
      On May 11, 2020, the National Institutes of Health (NIH) and the Bill & Melinda Gates Foundation (Gates Foundation) held an exploratory expert scientific roundtable to inform an NIH-Gates Foundation collaboration on the ...

    • Safe and efficient high dimensional motion planning in space-time with time parameterized prediction 

      Li, Shen; Shah, Julie A (IEEE, 2019)
      In this work, we propose an algorithm that can plan safe and efficient robot trajectories in real time, given time-parameterized motion predictions, in order to avoid fast-moving obstacles in human-robot collaborative ...

    • Safe and Efficient Tetrazole Synthesis in a Continuous Flow Microreactor 

      Palde, Prakash B.; Jamison, Timothy F. (Wiley Blackwell, 2011-03)
      Safer flow: The synthesis of 5-substituted tetrazoles in flow (see scheme) is safe, efficient, scalable, requires no metal promoter, and uses a near-equimolar amount of NaN[subscript 3], yet nonetheless displays a broad ...

    • Safe Asset Scarcity and Aggregate Demand 

      Farhi, Emmanuel; Gourinchas, Pierre-Olivier; Caballero, Ricardo J (American Economic Association, 2016-05)
      We explore the consequences of safe asset scarcity on aggregate demand in a stylized IS-LM/Mundell Fleming style environment. Acute safe asset scarcity forces the economy into a "safety trap" recession. In the open economy, ...

    • The Safe Assets Shortage Conundrum 

      Farhi, Emmanuel; Gourinchas, Pierre-Olivier; Caballero, Ricardo J (American Economic Association, 2017-08)
      A safe asset is a simple debt instrument that is expected to preserve its value during adverse systemic events. The supply of safe assets, private and public, has historically been concentrated in a small number of advanced ...