Browsing MIT Open Access Articles by Author "Caballero, Francisco"
Now showing items 1-2 of 2
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Recent discoveries and applications involving small-molecule microarrays
Hong, Jiyoung A; Neel, Dylan V; Wassaf, Dina; Caballero, Francisco; Koehler, Angela Nicole (Elsevier BV, 2013-11)High-throughput and unbiased binding assays have proven useful in probe discovery for a myriad of biomolecules, including targets of unknown structure or function and historically challenging target classes. Over the past ... -
Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription
Struntz, Nicholas B.; Chen, Andrew I; Deutzmann, Anja; Wilson, Robert M.; Stefan, Eric; e.a. (Elsevier BV, 2019-05)The transcription factor Max is a basic-helix-loop-helix leucine zipper (bHLHLZ) protein that forms homodimers or interacts with other bHLHLZ proteins, including Myc and Mxd proteins. Among this dynamic network of interactions, ...