Browsing MIT Open Access Articles by Author "Raab, Monika"
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CEACAM1 regulates TIM-3-mediated tolerance and exhaustion
Huang, Yu-Hwa; Zhu, Chen; Kondo, Yasuyuki; Anderson, Ana C.; Gandhi, Amit; e.a. (Nature Publishing Group, 2014-10)T-cell immunoglobulin domain and mucin domain-3 (TIM-3, also known as HAVCR2) is an activation-induced inhibitory molecule involved in tolerance and shown to induce T-cell exhaustion in chronic viral infection and ...