| dc.contributor.author | Stephanopoulos, Gregory | |
| dc.date.accessioned | 2017-04-06T20:35:01Z | |
| dc.date.available | 2017-04-06T20:35:01Z | |
| dc.date.issued | 2015-08 | |
| dc.date.submitted | 2015-08 | |
| dc.identifier.issn | 09581669 | |
| dc.identifier.uri | http://hdl.handle.net/1721.1/107921 | |
| dc.description.abstract | Measuring intracellular metabolism has increasingly led to important insights in biomedical research. [superscript 13]C tracer analysis, although less information-rich than quantitative [superscript 13]C flux analysis that requires computational data integration, has been established as a time-efficient method to unravel relative pathway activities, qualitative changes in pathway contributions, and nutrientcontributions. Here, we review selected key issues in interpreting [superscript 13]C metabolite labeling patterns, with the goal of drawing accurate conclusions from steady state and dynamic stable isotopic tracer experiments | en_US |
| dc.language.iso | en_US | |
| dc.publisher | Elsevier | en_US |
| dc.relation.isversionof | http://dx.doi.org/10.1016/j.copbio.2015.02.003 | en_US |
| dc.rights | Creative Commons Attribution-NonCommercial-NoDerivs License | en_US |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | en_US |
| dc.source | PMC | en_US |
| dc.title | A roadmap for interpreting 13C metabolite labeling patterns from cells | en_US |
| dc.type | Article | en_US |
| dc.identifier.citation | Buescher, Joerg M et al. “A Roadmap for Interpreting 13C Metabolite Labeling Patterns from Cells.” Current Opinion in Biotechnology 34 (2015): 189–201. | en_US |
| dc.contributor.department | Massachusetts Institute of Technology. Department of Chemical Engineering | en_US |
| dc.contributor.mitauthor | Stephanopoulos, Gregory | |
| dc.relation.journal | Current Opinion in Biotechnology | en_US |
| dc.eprint.version | Author's final manuscript | en_US |
| dc.type.uri | http://purl.org/eprint/type/JournalArticle | en_US |
| eprint.status | http://purl.org/eprint/status/PeerReviewed | en_US |
| dspace.orderedauthors | Buescher, Joerg M; Antoniewicz, Maciek R; Boros, Laszlo G; Burgess, Shawn C; Brunengraber, Henri; Clish, Clary B; DeBerardinis, Ralph J; Feron, Olivier; Frezza, Christian; Ghesquiere, Bart; Gottlieb, Eyal; Hiller, Karsten; Jones, Russell G; Kamphorst, Jurre J; Kibbey, Richard G; Kimmelman, Alec C; Locasale, Jason W; Lunt, Sophia Y; Maddocks, Oliver DK; Malloy, Craig; Metallo, Christian M; Meuillet, Emmanuelle J; Munger, Joshua; Nöh, Katharina; Rabinowitz, Joshua D; Ralser, Markus; Sauer, Uwe; Stephanopoulos, Gregory; St-Pierre, Julie; Tennant, Daniel A; Wittmann, Christoph; Vander Heiden, Matthew G; Vazquez, Alexei; Vousden, Karen; Young, Jamey D; Zamboni, Nicola; Fendt, Sarah-Maria | en_US |
| dspace.embargo.terms | N | en_US |
| dc.identifier.orcid | https://orcid.org/0000-0001-6909-4568 | |
| mit.license | PUBLISHER_CC | en_US |
