This is an archived course. A more recent version may be available at ocw.mit.edu.

 

Calendar

The calendar below provides information on the course's lecture (L) and recitation (R) sessions.

DAL: Prof. Douglas Lauffenburger
FMW: Prof. Forest White
KA: Kathyryn Armstrong
SW: Shan Wu
CR: Craig Rothman

SES # INSTRUCTORS TOPICS KEY DATES
L1 FMW Introduction - 20, 20.320, Biology, Mechanisms, and Modeling Protein Interactions  
R1 KA/SW/CR Recitation 1  
L2 FMW Protein Interactions II

Thermodynamics of Monovalent Interactions
Problem set 1 assigned
L3 FMW Monovalent Interactions  
R2   Recitation 2  
L4 FMW Fractional Saturation Problem set 1 due

Problem set 2 assigned
L5 FMW Measurement Techniques for Kd  
R3 KA/SW/CR Recitation 3  
L6 FMW Perturbations to Monovalent Interactions Problem set 2 due

Problem set 3 assigned
L7 FMW Perturbations II - Solution Effects  
R4   Recitation 4  
L8 FMW Multivalent Binding Problem set 3 due

Problem set 4 assigned
L9 FMW Cooperativity  
R5   Recitation 5  
L10 FMW Avidity and Effective Concentration Problem set 4 due
R6 CR/SW Recitation 6  
  FMW Exam 1 - Monovalent Binding, Measurement, Perturbations, Multivalent Binding, Cooperativity  
L11 FMW Enzyme Kinetics I  
L12 FMW Enzyme Kinetics II  
R7   Recitation 7  
R8   Recitation 8  
L13 DAL Enzyme Inhibitors Problem set 5 assigned
L14 DAL Integrating Pathways Into Networks  
R9   Recitation 9  
L15 DAL Ligand-Receptor Interactions Problem set 5 due

Problem set 6 assigned
L16 DAL Endocytic Trafficking I  
R10   Recitation 10  
R11 CR/SW Recitation 11 Problem set 6 due
  DAL/FMW Exam 2 - Avidity, Enzymes, and Networks  
L17 DAL Endocytic Trafficking II Problem set 7 assigned
L18 DAL Biomolecular Reactions in Context of Transport  
R12   Recitation 12  
L19 DAL Fundamentals of Molecular Transport Problem set 7 due

Problem set 8 assigned
L20 DAL Reaction Terms and Approximations  
R13   Recitation 13  
L21 DAL Macroscopic and Microscopic Effects of Diffusion Problem set 8 due

Problem set 9 assigned (ungraded)
L22 DAL Autocrine/Paracrine Cell-cell Communication  
R14   Recitation 14  
L23 DAL Cell Population Dynamics I: Cell Growth, Death, Differentiation, and Product Synthesis  
L24 DAL Cell Population Dynamics II: Application to Tissues and Bioreactors  
  DAL Exam 3 - Test Accumulated Knowledge (Emphasis on Mechanisms Underlying Biomolecular Systems)