This is an archived course. A more recent version may be available at ocw.mit.edu.

 

Assignments

ASSIGNMENTS SOLUTIONS SUPPORTING FILES
Problem Set 1 (PDF) (This resource may not render correctly in a screen reader.PDF)  
Problem Set 2 (PDF) (This resource may not render correctly in a screen reader.PDF) pset2_data.htm (HTM)
Problem Set 3 (PDF) (This resource may not render correctly in a screen reader.PDF) hw3.m (M)

C_function.m (M)
Problem Set 4 (PDF) (This resource may not render correctly in a screen reader.PDF) pset4_data.htm (HTM)
Problem Set 5 (PDF) (This resource may not render correctly in a screen reader.PDF)  
Problem Set 6 (PDF) (PDF) pset6_matlab.m (M)

KinaseCascade.m (M)

Ferrell, J. E., Jr. "Tripping the switch fantastic: how a protein kinase cascade can convert graded inputs into switch-like outputs." Trends Biochem Sci 21, no. 12 (December 1996): 460-6.

Kuhl, P. R., and L. G. Griffith-Cima. "Tethered epidermal growth factor as a paradigm for growth factor-induced stimulation from the solid phase." Nat Med 2, no. 9 (September 1996): 1022-7.
Problem Set 7 (PDF) (PDF) gross_lodish.m (M)

pset7_matlab.m (M)

Gross, A. W., and H. F. Lodish. "Cellular trafficking and degradation of erythropoietin and novel erythropoiesis stimulating protein (NESP)." J Biol Chem 281, no. 4 (January 27, 2006): 2024-32. Epub (November 11, 2005).
Problem Set 8 (PDF) (This resource may not render correctly in a screen reader.PDF) myfun.m (M)

demo_fsolve.m (M)

pset8_matlab.m (M)
Problem Set 9 (PDF) (PDF) Sarkar, C. A., and D. A. Lauffenburger. "Cell-level pharmacokinetic model of granulocyte colony-stimulating factor: implications for ligand lifetime and potency in vivo." Mol Pharmacol 63, no. 1 (January 2003): 147-58.