MIT Theses: Recent submissions
Now showing items 13-15 of 65109
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Reconstructing Cross-Species Ancestral Adeno-Associated Viruses for Enhanced Gene Therapy Delivery
(Massachusetts Institute of Technology, 2025-09)Adeno-associated viruses (AAV) are one of the most promising vectors for gene therapy because of their established safety, low immunogenicity, and capability to achieve sustained gene expression. However, many naturally ... -
Intercellular flow-mediated force relaxation measurement on the three-dimensional multicellular tissue
(Massachusetts Institute of Technology, 2024-05)Three-dimensional (3D) multicellular tissues are prevailing over 2D monolayer or single cells; their mechanical properties like stiffness, surface tension, and viscosity have been shown to relate to diseases like fibrosis ... -
Generating Unprecedented Extreme Scenarios with Limited Data
(Massachusetts Institute of Technology, 2025-09)Quantifying and predicting rare and extreme events persists as a crucial yet challenging task in understanding complex dynamical systems, ubiquitous in science and engineering. Many practical challenges arise from the ...
