Search
Now showing items 291-296 of 296
Genetic analysis of the neuronal integrated stress response in developmental plasticity and organismal physiology of C. elegans
(Massachusetts Institute of Technology, 2017)
The genetic study of the C. elegans dauer developmental decision has served as an experimental paradigm for understanding how environmental cues influence organismal physiology through evolutionarily conserved neuroendocrine ...
CRISPR-mediated interrogation of small cell lung cancer
(Massachusetts Institute of Technology, 2018)
Small cell lung cancer (SCLC) is a highly aggressive neuroendocrine lung carcinoma that remains among the most lethal of solid tumor malignancies. Despite decades of research, treatment outcomes for SCLC remain very poor, ...
Co-targeting among microRNAs is widespread and enriched in the brain
(Massachusetts Institute of Technology, 2019)
MicroRNAs (miRNAs) play roles in diverse developmental processes and cellular differentiation. Distinct miRNAs have hundreds to thousands of conserved binding sites in mRNAs, but typically exert only modest repression on ...
Functional changes in connectivity induced by differential manipulations of activity in Drosophila tonic versus phasic motoneurons
(Massachusetts Institute of Technology, 2020)
Structural and functional plasticity induced by neuronal competition is a common feature of developing nervous systems. However, the rules governing how postsynaptic cells differentiate between presynaptic inputs are ...
Studies on the biosynthesis of thiamine
(Massachusetts Institute of Technology, 1959)
The structure and properties of the trichocysts of paramecium.
(Massachusetts Institute of Technology, 1945)