MIT Open Access Articles: Recent submissions

Now showing items 100-102 of 55108

    • Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy 

      Rawat, Vipin; DeLear, Patrick; Prashanth, Prarthana; Ozgurses, Mete Emir; Tebeje, Anteneh; e.a. (American Society for Clinical Investigation, 2024-05-30)
      The nonphysiological nutrient levels found in traditional culture media have been shown to affect numerous aspects of cancer cell physiology, including how cells respond to certain therapeutic agents. Here, we comprehensively ...

    • Metabolic Engineering of E. coli for Enhanced Diols Production from Acetate 

      Ricci, Luca; Cen, Xuecong; Zu, Yuexuan; Antonicelli, Giacomo; Chen, Zhen; e.a. (American Chemical Society, 2025-04-18)
      Effective employment of renewable carbon sources is highly demanded to develop sustainable biobased manufacturing. Here, we developed Escherichia coli strains to produce 2,3-butanediol and acetoin (collectively referred ...

    • Constant Degree Networks for Almost-Everywhere Reliable Transmission 

      Bafna, Mitali; Minzer, Dor (ACM|Proceedings of the 57th Annual ACM Symposium on Theory of Computing, 2025-06-15)
      In the almost-everywhere reliable message transmission problem, introduced by [Dwork, Pippenger, Peleg, Upfal’86], the goal is to design a sparse communication network G that supports efficient, fault-tolerant protocols ...