Doctoral Theses: Recent submissions
Now showing items 58-60 of 23327
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Development of a targeted lipid nanoparticle platform for in vivo RNA delivery to hematopoietic stem and progenitor cells
(Massachusetts Institute of Technology, 2025-09)Hematopoietic stem cells (HSCs) are rare cells residing in the bone marrow that are responsible for the generation and maintenance of the body’s immune system through a process known as hematopoiesis. Because of their ... -
A 3D human liver tissue model of the hepatobiliary junction
(Massachusetts Institute of Technology, 2025-09)Cholestasis, or disruption in bile flow, is a poorly-understood feature of many liver diseases and is a well-established indication for liver transplant. Despite this clinical significance, many tissue engineering strategies ... -
Modeling and Control of a Continuous Lyophilizer
(Massachusetts Institute of Technology, 2025-09)Lyophilization, or vacuum freeze-drying, is a separations process in pharmaceutical manufacturing used to stabilize aqueous drug products by removing nearly all the water at cryogenic temperatures. This process is often ...
