Doctoral Theses: Recent submissions
Now showing items 124-126 of 23394
-
Development of Modular Strategies for Enhancing Biomanufacturing in Komagataella phaffii
(Massachusetts Institute of Technology, 2025-09)The landscape of protein therapeutics is advancing towards more complex modalities that offer greater medical potential but present significant challenges to existing biomanufacturing frameworks. Alongside these technical ... -
Development of a targeted lipid nanoparticle platform for in vivo RNA delivery to hematopoietic stem and progenitor cells
(Massachusetts Institute of Technology, 2025-09)Hematopoietic stem cells (HSCs) are rare cells residing in the bone marrow that are responsible for the generation and maintenance of the body’s immune system through a process known as hematopoiesis. Because of their ... -
A 3D human liver tissue model of the hepatobiliary junction
(Massachusetts Institute of Technology, 2025-09)Cholestasis, or disruption in bile flow, is a poorly-understood feature of many liver diseases and is a well-established indication for liver transplant. Despite this clinical significance, many tissue engineering strategies ...
