Browsing Doctoral Theses by Title
Now showing items 1914-1933 of 22097
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¹³C-metabolic flux analysis of recombinant yeasts for biofuels applications
(Massachusetts Institute of Technology, 2015)Fossil fuels have powered the transportation industry since the Industrial Revolution. However, rising transportation energy demand and new knowledge about the environmental impact of burning fossil fuels have motivated ... -
c-Myc regulates transcriptional pause release and is a global amplifier of transcription
(Massachusetts Institute of Technology, 2012)Elevated expression of the c-Myc transcription factor occurs frequently in human cancers and is associated with tumor aggression and poor clinical outcome. However, the predominant mechanism by which c-Myc regulates global ... -
C. elegans apoptosis : CED-4 translocation and involvement in a model of mucolipidosis type IV human lysosomal storage disorder
(Massachusetts Institute of Technology, 2002)The process of programmed cell death is important in the development and homeostasis of multicellular organisms. The conserved morphological events of this process have been termed apoptosis. The molecular mechanisms of ... -
The C. elegans class A synthetic multivulva genes inhibit ectopic RAS-mediated vulval development by tightly restricting expression of lin-3 EGF
(Massachusetts Institute of Technology, 2011)The class A and B synthetic multivulva (synMuv) genes of C. elegans redundantly antagonize an EGF/Ras pathway to prevent ectopic vulval induction. The class B synMuv genes encode many proteins known to remodel chromatin ... -
The C. elegans heterochronic pathway controls the timing of NAB/EGR-mediated terminal differentiation and the onset of adulthood
(Massachusetts Institute of Technology, 2011)Most animals pass through a series of juvenile stages on their way from embryo to adult. These stages represent periods of time in which stage-specific developmental processes occur. At the end of development, the organism ... -
A C. elegans histone methyltransferase promotes spermatocyte gene expression, spermatid production and fertility
(Massachusetts Institute of Technology, 2017)To better understand the tissue-specific regulation of chromatin state in cell-fate determination and development, we defined the tissue-specific expression of all 36 lysine methyltransferase (KMT) genes by endogenous mRNA ... -
C. elegans integrates food, stress, and hunger signals to coordinate motor activity
(Massachusetts Institute of Technology, 2008)In the presence of a bacterial food source, the small nematode C. elegans greatly reduces its rate of locomotion. While mechanical agitation greatly stimulates the locomotion of well-fed animals on bacteria, it does not ... -
Cacophonous geographies : the symbolic and material landscapes of race
(Massachusetts Institute of Technology, 2012)Since the devastation of Hurricane Katrina in 2005 and the election of President Barack Obama in 2008, the country has struggled with questions regarding the salience of racial inequality. While the days following Katrina ... -
CAD systems and communication in design engineering--a test of the information processing model
(Massachusetts Institute of Technology, 1990) -
Cadmium, a toxin and nutrient for marine phytoplankton
(Massachusetts Institute of Technology, 1995) -
The CAFE experiment : a joint seismic and MT investigation of the Cascadia subduction system
(Massachusetts Institute of Technology, 2013)In this thesis we present results from inversion of data using dense arrays of collocated seismic and magnetotelluric stations located in the Cascadia subduction zone region of central Washington. In the migrated seismic ... -
Caged phosphopeptides and phosphoproteins : agents in unraveling complex biological pathways
(Massachusetts Institute of Technology, 2005)Within cellular signaling, protein phosphorylation is the post-translational modification most frequently used to regulate protein activity. Protein kinases and phosphoprotein phosphatases generate and terminate these ... -
Caged phosphopeptides and phosphoproteins : probes to dissect the role of phosphorylation in complex signaling pathways
(Massachusetts Institute of Technology, 2007)Protein phosphorylation is a central regulatory mechanism in signal transduction pathways and cellular migration. Current genetic strategies for the study of phosphorylation, including gene knockout and point mutation, are ... -
Cakewalking into representation : Gabriele Münter's America travels (1898-1900) and art of dailiness
(Massachusetts Institute of Technology, 2008)This study explores the fashioning of Gabriele Münter as a German modernist with a focus on the eclipse of her struggles in coming to representation, the rich complexity of her processes, and the importance of dailiness ... -
Calculating bully : explaining Chinese coercion
(Massachusetts Institute of Technology, 2018)Since 1990, China has used coercion for territorial disputes, foreign arms sales to Taiwan, and foreign leaders' meetings with the Dalai Lama, despite adverse implications for its international image. China is also curiously ... -
A calculation of the energy bands of the graphite crystal by means of the tight-binding method
(Massachusetts Institute of Technology, 1956) -
Calculations of viscoelastic flow in a journal bearing
(Massachusetts Institute of Technology, 1986) -
Caledonian structure, metamorphism, geochronology, and tectonics of the Sitas-Singis area, Sweden
(Massachusetts Institute of Technology, 1987) -
Calendering of an elastic-viscous material
(Massachusetts Institute of Technology, 1955) -
Calibration and Utilization of High-Fidelity Two-Qubit Operations
(Massachusetts Institute of Technology, 2023-02)Over the past two decades, impressive strides have been made in the field of quantum computing. Quantum advantage has been reported, and there is now an ecosystem of cloud-based quantum processors and companies interested ...