This is an archived course. A more recent version may be available at ocw.mit.edu.

Readings

[GES] = Buy at MIT Press Buy at Amazon Schneider, G. E. Brain Structure and Its Origins: in Development and in Evolution of Behavior and the Mind. MIT Press, 2014. ISBN: 9780262026734..

Additional Readings

[LWS] = Buy at Amazon Swanson, Larry W. Brain Architecture, Understanding the Basic Plan. New York, NY: Oxford University Press, 2002. ISBN: 9780195105056.

[JMA] = Buy at Amazon Allman, John Morgan. Evolving Brains. New York, NY: Scientific American Library: Distributed by W. H. Freeman and Co., 1999. ISBN: 9780716750765.

[JHMF] = Buy at Amazon Nauta, Walle J. H., and Michael Feirtag. Fundamental Neuroanatomy. New York, NY: Freeman, 1986. ISBN: 9780716717232.

[GFS] = Buy at Amazon Striedter, Georg F. Principles of Brain Evolution. Sunderland, MA: Sinauer Associates, 2004. ISBN: 9780878938209.

[PB] = Buy at Amazon Brodal, Per. The Central Nervous System, Structure and Function. 3rd ed. New York, NY: Oxford University Press, 2003. ISBN: 9780195165609.

[WHAB] = Buy at Amazon Butler, Ann B., and William Hodos. Comparative Vertebrate Neuroanatomy: Evolution and Adaptation. New York, NY: Wiley-Liss, 1996. ISBN: 9780471888895.

[JWDP] = Buy at Amazon Purves, Dale, and Jeff W. Lichtman. Principles of Neural Development. Sunderland, MA: Sinauer Associates, 1985. ISBN: 9780878937448.

[MM] = Buy at Amazon Mesulam, M-Marsel, ed. Principles of Behavioral and Cognitive Neurology. New York, NY: Oxford University Press, 2000. ISBN: 9780195134759.

SES # TOPICS READINGS
1-2 Introduction: brain orientation, primitive cellular activities

Chapters 1 and 2 [GES]

Chapter 1 [JMA]

Chapter 1 [JHMF]
[Recommended only]

Chapters 1 and 2 [LWS]
3-4 Steps to the CNS of chordates

Chapters 3 and 4 [GES]

Chapter 2 [JMA]
[Chapters 3 and 4 recommended only]

Chapter 3 [LWS]
[Recommended only]

Chapter 2 [GFS]
[Assigned pp. 37-44]
5-6 Specializations in CNS evolution

Chapters 5, 6, and 7 [GES]

Chapter 3 [GFS]
[Recommended pp. 81-91]

Chapter 4 [JHMF]
[Chapter 3 recommended only]

Chapter 4 [LWS]
[Recommended only]
7-8 Spinal cord development and anatomy

Chapters 8 and 9 [GES]

Chapter 4a [LWS]
[Chapter 4b recommended only]

Chapter 1 [JWDP]

pp. 220-223, Figure 7.1 [GFS]
9 Autonomic nervous system. Differentiation of the brain vesicles: Intro. To hindbrain and segmentation

Chapters 9a, 10, 11, and 12 [GES]

Chapter 5 [JHMF]
[Chapters 10 and 11 recommended only]

Chapter 5 [JMA]

Chapters 7, 9, and 10 [WHAB]
[pp. 134-140 recommended only]

Buy at Amazon Wolpert, Lewis, et al. Principles of Development. New York, NY: Oxford University Press, 2006, section on Homeobox Genes. ISBN: 9780199275373.

Buy at Amazon Nolte, John, et al. The Human Brain. St. Louis, MO: Mosby, 2002, Table 12-2. ISBN: 9780323013208.
10 Differentiation of the brain vesicles: Hindbrain and cranial nerves, specializations Same as Ses #9
11 Differentiation of the brain vesicles: Developmental distortions; evolution of midbrain and forebrain; midbrain organization Same as Ses #9
12 Differentiation of the brain vesicles: Vertebrate forebrain evolution and organization Same as Ses #9
13-14 CNS differentiation: Axon growth

Chapter 13 [GES]

Chapters 4 and 5 [JWDP]

Buy at Amazon Zigmond, Michael J., et al., eds. "Growth Cones and Axon Pathfinding." In Fundamental Neuroscience. Illustrations by Robert S. Woolley. Part III. San Diego, CA: Academic Press, 1998, pp. 417-517, 519-546, and 547-654. ISBN: 9780127808703.
15-17 Motor systems

Chapters 14, 15, and 16 [GES]

Chapter 6A [LWS]
[Chapters 5 and 6B recommended only]

Chapter 7 [JHMF]

Chapter 7 [GFS]
[pp. 245-253 recommended only]
17-18 Brain states

Chapter 17 [GES]
20 Gustatory and olfactory systems

Chapters 18 and 19 [GES]

Chapter 10 [PB]

Lois, C., J. M. Garcia-Verdugo, and A. Alvarez-Buylla. "Chain Migration of Neuronal Precursors." Science 271 (1996): 978-981.

Shown in lectures

Buy at Amazon Cajal, S. Ramón y. Vol. 2 of Histology of the Nervous System of Man and Vertebrates. Translated by Neely Swanson and Larry W. Swanson. New York, NY: Oxford University Press, 1995. ISBN: 9780195074017. [See drawings in chapters 28-30.]

Recommended

Chapter 5 [GFS]

Alvarez-Buylla, A., and J. M. Garcia-Verdugo. "Neurogenesis in Adult Subventricular Zone." J Neurosci 22 (2002): 629-634.

Malnic, B., J. Hirono, T. Sato, and L. Buck. "Combinatorial Receptor Codes for Odors." Cell 96 (1999): 713-723.
21-23 Visual systems

Chapters 20, 21, and 22 [GES]

Chapter 6 [JMA]

Chapters 5 and 6. Figures 7.14, 7.15, and 7.16 [GFS]

Chapters 18, 20, 22, 25, and 26 [WHAB]
24-25 Auditory and related sensory

Chapter 23 [GES]

Chapter 5 [JMA]

Chapters 5 and 8. Figure 8.10 [GFS]
[pp. 255-258 and 268-287 recommended only]

Chapter 28, pp. 148-152 [WHAB]
[Recommended only]
26 Introduction to the forebrain

Chapter 24 [GES]

Chapter 8a [GFS]

Chapter 5 [JMA]

Chapter 13 [JHMF]

Chapter 19 [WHAB]
[Recommended only]

Fliessbach, K., et al. "Social Comparison Affects Reward-Related Brain Activity in the Human Ventral Striatum." Science 318 (2007): 1305-1308.
27-29 Hypothalamus and limbic system 1

Chapter 25 [GES]

Chapters 26 and 27 [GFS]

Chapters 8 and 9 [JHMF]

Chapter 19 [PB]

Chapters 6B and 7 [LWS]

Chapter 1 [MM]

Giesler, G. J., Jr., J. T. Katter, and R. J. Dado. "Direct Spinal Pathways to the Limbic System for Nociceptive Information." Trends in Neuroscience 17 (1994): 244-250.

Swaab, D. F., and M. A. Hofman. "Sexual Differentiation of the Human Hypothalamus in Relation to Gender and Sexual Orientation." Trends in Neuroscience 18 (1995): 264-270.

Nottebohm, F. "From Bird Song to Neurogenesis." Scientific American (February 1989): 74-79.

Buy at Amazon Baum, M. J. "Psychosexual Development." Chapter 47 in Fundamental Neuroscience. Illustrations by Robert S. Woolley. Part III. San Diego, CA: Academic Press, 1998, pp. 1229-1244, Box 47.2, and 47.3. ISBN: 9780127808703.

Recommended

Toran-Allerand, C. D. "Mechanisms of Estrogen Action During Neural Development: Mediation by Interactions with the Neurotrophins and their Receptors?" J Steroid Biochem Mol Biol 56 (1997): 169-178.

———. "Organotypic Culture of the Developing Cerebral Cortex and Hypothalamus: Relevance to Sexual Differentiation." Psychoneuroendocrinology 16 (1991): 7-24.

Reisert, I., V. Han, E. Lieth, D. Toran-Allerand, C. Pilgrim, and J. Lauder. "Sex Steroids Promote Neurite Growth in Mesencephalic Tyrosine Hydroxylase Immunoreactive Neurons in Vitro." International Journal of Developmental Neuroscience 5 (1987): 91-98.

Johnson, F., and S. W. Bottjer. "Differential Estrogen Accumulation among Populations of Projections Neurons in the Higher Vocal Center of Male Canaries." J Neurobiology 26: 87-108.

Brown, S. D., and S. W. Bottjer. "Testosterone-induced Changes in Adult Canary Brain are Reversible." J Neurobiology 24 (1993): 627-640.

Brown, S. D., F. Johnson, and S. W. Bottjer. "Neurogenesis in Adult Canary Telencephalon is Independent of Gonadal Hormone Levels." J Neuroscience 13 (1993): 2024-2032.

Bottjer, S. W., and T. P. Dignan. "Joint Hormonal and Sensory Stimulation Modulate Neuronal Number in Adult Canary Brains." J Neurobiology 19 (1998): 624-635.
30-32 Hypothalamus and limbic system 2

Chapter 28 [GES]

Chapters 5 and 8 [GFS]

Chapter 20 [PB]

Chapter 30 [WHAB]
[Read section 'Evolutionary perspective' to get a flavor of comparative work]

Recommended

Chapter 1 [MM]

Chapter 29 [GFS]

Additional readings

J. Stevens, et al. "Deep Temporal Stimulation in Man: Long Latency, Long Lasting Psychological Changes." Arch Neurol 21, no. 2 (1969): 157-169.
33-34 Corpus striatum

Chapters 30 and 31 [GES]

pp. 99, Figure 48 [JHMF]
[pp. 97-101 recommended only]

Chapter 8C [GFS]

Chapter 13 [PB]

Chapter 1 [MM]

Additional readings

Olanow, C. W., J. H. Kordower, and T. B. Freeman. "Fetal Nigral Transplantation as a Therapy for Parkinson's Disease." Trends in Neuroscience 19 (1996): 103-109.

Kempermann, G., and F. H. Gage. "New Nerve Cells for the Adult Brain." Sci American 280 (1999): 48-53.

Olanow, C. W., et al. "A Double-Blind Controlled Trial of Bilateral Fetal Nigral Transplantation in Parkinson's Disease." Annals of Neurology 54 (2003): 403-414.
35-39 Neocortex

Chapters 32, 33, 34, and 35 [GES]

Chapter 7 [JMA]

Additional Readings

Chapters 13 and 16 [JHMF]

Chapter 21 [PB]

Chapter 4 [JWDP]

Rakic, P. A. "Small Step for the Cell, a Giant Leap for Mankind: A Hypothesis of Neocortical Expansion During Evolution." Trends in Neurosciences 18 (1995): 383-388.

Recommended as more advanced readings

Chapter 9 [GFS]

Chapter 1 [MM]

Finlay, B. L., and R. B. Darlington. "Linked Regularities in the Development and Evolution of Mammalian Brains." Science 268 (1995): 1578-1584.

Chapter 4 [PB]

Bonhoeffer, T. "Neurotrophins and Activity-Dependent Development of the Neocortex." Current Opinion in Neurobiology 6 (1996): 119-126.

Sur, M., A. Angelucci, and J. Sharma. "Rewiring Cortex: The Role of Patterned Activity in Development and Plasticity of Neocortical Circuits." J Neurobiol 41 (1999): 33-43.

Bai, W., M. Ishida, M. Okabe, and Y. Arimatsu. "Role of the Protomap and Target Derived Signals in the Development of Intrahemispheric Connections." Cerebral Cortex 16 (2006): 124-135.