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Now showing items 51-56 of 56
Simulation modeling to predict drug pipeline throughput in early pharmaceutical R&D
(Massachusetts Institute of Technology, 2010)
With high costs and growing concern about research and development (R&D) productivity, the pharmaceutical industry is under pressure to efficiently allocate R&D funds. Nonetheless, pharmaceutical R&D involves considerable ...
Implementing a new organization to manage manufacturing technology innovation
(Massachusetts Institute of Technology, 2003)
The purpose of this research is to provide an academic, external perspective to facilitate the implementation and development of a new internal organization for Raytheon Missile Systems (RMS) with a focus on strategy and ...
Enterprise design for dynamic complexity : architecting & engineering organizations using system & structural dynamics
(Massachusetts Institute of Technology, 2004)
As the business world is neither linear nor static, the mastery of its "chaotic" nonlinear dynamics lies at the heart of finding high-leverage policies that return uncommon benefits for marginal costs. Today's global ...
A study of the Mighty Motors operating system : making sustainable improvements at a powertrain manufacturing facility
(Massachusetts Institute of Technology, 2004)
Many manufacturing companies are developing their own production or operating system, particularly in an effort to duplicate the widely renowned Toyota Production System. Toyota has demonstrated its potential for improving ...
The role of assessment in a lean transformation
(Massachusetts Institute of Technology, 2008)
When starting the journey to become a Lean company, companies commonly face the problem of understanding how to manage a Lean transformation. Often times, the first step in managing a Lean transformation is to understand ...
A network planning process and inventory strategy for high-mix low-volume markets
(Massachusetts Institute of Technology, 2012)
From June to December 2011, the impact of rapid international expansion on the Global Supply Chain organization at Amgen - one of the world's leading human therapeutics companies in the biotechnology industry - was ...