MIT Libraries: Recent submissions
Now showing items 109-111 of 65464
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Noncovalent PROTAC Antibody Drug Conjugates
(Massachusetts Institute of Technology, 2026-02)Proteolysis Targeting Chimeras (PROTACs) are a new class of heterobifunctional drugs that induce proximity between an E3 ligase and a given protein of interest (POI), causing the POI to be ubiquitinated and targeted for ... -
Interpolation Methods in Random Optimization and Deep Learning
(Massachusetts Institute of Technology, 2026-02)This thesis studies three problems in high-dimensional probability and statistics: (1) the densest subgraph problem in dense random graphs, where the goal is to estimate and recover the subgraph with the highest edge ... -
Predictive Methods and Datasets for Thermodynamic and Kinetic Modeling of Ionic Solutes
(Massachusetts Institute of Technology, 2026-02)The ability to quantitatively describe ionization phenomena is essential to designing medicines, developing novel materials, and modeling the time-evolution of many relevant liquid-phase chemical systems. In liquid phase ...


