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Hybrid flow data center network architecture design and analysis
(Massachusetts Institute of Technology, 2017)
In this thesis, we propose a hybrid flow network architecture for future data center. The hybrid flow architecture has its origins in the early 1990s with studies on all-optical networks and fiber-optical computer networks. ...
Three essays on entrepreneurial quality
(Massachusetts Institute of Technology, 2017)
This dissertation introduces a new method to measure entrepreneurial quality and applies it to three questions of theoretical interest in entrepreneurship. The dissertation is presented in five chapters. Chapter 1 is an ...
Stimuli-responsive self-assembling materials comprising amphiphilic copolymers for localized remotely triggered therapeutic delivery
(Massachusetts Institute of Technology, 2017)
The ability to introduce therapeutic at a specified location and time to a healing traumatic wound deep within the body by external non-invasive stimulus could provide great long-term benefit to patients. In this work, we ...
Regulatory systems for the robust control of engineered genetic programs
(Massachusetts Institute of Technology, 2017)
The ability to engineer complex genetic programs could have a huge impact on many industries, yielding organisms that can respond to their environment and perform functions relevant to manufacturing, agriculture, and ...
Joint practical deliberation
(Massachusetts Institute of Technology, 2017)
Joint practical deliberation is the activity of deciding together what to do. In this dissertation, I argue that several speech acts that we can use to alter our moral obligations - promises, offers, requests, demands, ...
Development and analysis of high order neutron transport-depletion coupling algorithms
(Massachusetts Institute of Technology, 2017)
The coupling of depletion and neutron transport together creates a particularly challenging mathematical problem. Due to the stiffness of the ODE, special algorithms needed to be developed to minimize the number of transport ...
Mechanically flexible vapor-deposited polymeric thin films for electrochemical devices
(Massachusetts Institute of Technology, 2017)
The concept of self-powered wearable electronic system has been emerging. Such a system consists of three units: an intelligent end-user electronic device for exporting functions, an energy generation/conversion device ...
Study of the differential compartmentation and functions of hexokinase isoforms and implications for cancer metabolism
(Massachusetts Institute of Technology, 2017)
Selectivity is a very important consideration when designing cancer treatment. Therefore, targeting cancer-specific isoforms of key metabolic enzymes is a very promising strategy. Elevated glucose consumption and lactate ...
Discovering physics and design trends from visual temporal structures
(Massachusetts Institute of Technology, 2017)
Living in a constantly changing world, we cannot help but notice the temporal regularities of visual changes around us. These changes can be irreversible governed by physical laws, such as glass bottles broken into pieces, ...
Functions of the conserved ribosome-bound protein Lso2 in translation and physiology
(Massachusetts Institute of Technology, 2017)
The ribosome is a highly conserved macromolecular machine that carries out translation, the synthesis of proteins from mRNAs, in all domains of life. The core ribosome interacts with dozens of general translation factors ...