20.441 / 2.79J / 3.96J / HST.522J Biomaterials-Tissue Interactions (BE.441), Fall 2003

Yannas, Ioannis; Spector, Myron

Author(s)

Yannas, Ioannis; Spector, Myron

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Alternative title

Biomaterials-Tissue Interactions (BE.441)

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Abstract

This course is an introduction to principles of materials science and cell biology underlying the design of medical implants, artificial organs, and matrices for tissue engineering. Topics include methods for biomaterials surface characterization and analysis of protein adsorption on biomaterials. Molecular and cellular interactions with biomaterials are analyzed in terms of unit cell processes, such as matrix synthesis, degradation, and contraction. It also covers mechanisms underlying wound healing and tissue remodeling following implantation in various organs. Other areas include tissue and organ regeneration; design of implants and prostheses based on control of biomaterials-tissue interactions; comparative analysis of intact, biodegradable, and bioreplaceable implants by reference to case studies. Also addressed are criteria for restoration of physiological function for tissues and organs.

Date issued

2003-12

URI

http://hdl.handle.net/1721.1/67471

Department

Massachusetts Institute of Technology. Department of Biological Engineering; Massachusetts Institute of Technology. Department of Civil and Environmental Engineering; Harvard University--MIT Division of Health Sciences and Technology; Massachusetts Institute of Technology. Department of Materials Science and Engineering; Massachusetts Institute of Technology. Department of Mechanical Engineering

Other identifiers

20.441-Fall2003

local: 20.441

local: 2.79J

local: 3.96J

local: HST.522J

local: IMSCP-MD5-e1af5d3c45e1048ac71d66822814879f

Keywords

medical implants, artificial organs, tissue engineering, matrix, biomaterials, protein adsorption, unit cell process, wound healing, tissue remodeling, tissue regeneration, organ regeneration, prosthesis, biodegradable, bioreplaceable implants, BE.441, 2.79J, 3.96J, HST.522J, 2.79, 3.96, HST.522

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