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7.341 DNA Damage Checkpoints: The Emergency Brake on the Road to Cancer, Fall 2007
(2007-12)
The DNA contained in human cells is under constant attack by both exogenous and endogenous agents that can damage one of its three billion base pairs. To cope with this permanent exposure to DNA-damaging agents, such as ...
7.341 The DNA Damage Response as a Target for Anti-Cancer Therapy, Fall 2008
(2008-12)
Cellular responses to DNA damage constitute one of the most important fields in cancer biology. In this class we will analyze classical and recent papers from the primary research literature to gain a profound understand ...