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Fluorescence assay for polymerase arrival rates
(Massachusetts Institute of Technology, 2004)
To engineer complex synthetic biological systems will require modular design, assembly, and characterization strategies. The RNA polymerase arrival rate (PAR) is defined to be the rate that RNA polymerases arrive at a ...
Cellular computation and communications using engineered genetic regulatory networks
(Massachusetts Institute of Technology, 2001)
In this thesis, I present an engineering discipline for obtaining complex, predictable, and reliable cell behaviors by embedding biochemical logic circuits and programmed intercellular communications into cells. To accomplish ...