| dc.contributor.author | Rai, Priyamvada | |
| dc.coverage.temporal | Fall 2007 | |
| dc.date.accessioned | 2023-03-13T13:41:35Z | |
| dc.date.available | 2023-03-13T13:41:35Z | |
| dc.date.issued | 2007-12 | |
| dc.identifier | 7.343-Fall2007 | |
| dc.identifier.other | 7.343 | |
| dc.identifier.other | IMSCP-MD5-36cf5efdd7c1215affef65c455e76217 | |
| dc.identifier.uri | https://hdl.handle.net/1721.1/148493 | |
| dc.description.abstract | This course will start with a survey of basic oxygen radical biochemistry followed by a discussion of the mechanisms of action of cellular as well as dietary antioxidants. After considering the normal physiological roles of oxidants, we will examine the effects of elevated ROS and a failure of cellular redox capacity on the rate of organismal and cellular aging as well as on the onset and progression of several major diseases that are often age-related. Topics will include ROS-induced effects on stem cell regeneration, insulin resistance, heart disease, neurodegenerative disorders, and cancer. The role of antioxidants in potential therapeutic strategies for modulating ROS levels will also be discussed. This course is one of many Advanced Undergraduate Seminars offered by the Biology Department at MIT. These seminars are tailored for students with an interest in using primary research literature to discuss and learn about current biological research in a highly interactive setting. Many instructors of the Advanced Undergraduate Seminars are postdoctoral scientists with a strong interest in teaching. | en |
| dc.language.iso | en-US | |
| dc.rights | This site (c) Massachusetts Institute of Technology 2023. Content within individual courses is (c) by the individual authors unless otherwise noted. The Massachusetts Institute of Technology is providing this Work (as defined below) under the terms of this Creative Commons public license ("CCPL" or "license") unless otherwise noted. The Work is protected by copyright and/or other applicable law. Any use of the work other than as authorized under this license is prohibited. By exercising any of the rights to the Work provided here, You (as defined below) accept and agree to be bound by the terms of this license. The Licensor, the Massachusetts Institute of Technology, grants You the rights contained here in consideration of Your acceptance of such terms and conditions. | en |
| dc.rights | Attribution-NonCommercial-ShareAlike 3.0 Unported | * |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/ | * |
| dc.subject | reactive oxygen species | en |
| dc.subject | oxygen | en |
| dc.subject | ROS | en |
| dc.subject | energy | en |
| dc.subject | mitochondria | en |
| dc.subject | cell signaling | en |
| dc.subject | anti-pathogen | en |
| dc.subject | oxidative damage | en |
| dc.subject | oncogene | en |
| dc.subject | antioxidant | en |
| dc.subject | insulin resistance | en |
| dc.subject | diabetes | en |
| dc.subject | stem cell | en |
| dc.subject | neurodegenerative | en |
| dc.subject | ischemic | en |
| dc.subject | ATP | en |
| dc.subject | pathways | en |
| dc.subject | NADPH | en |
| dc.subject | nox | en |
| dc.subject | psd | en |
| dc.subject | programmed cell death | en |
| dc.subject | apoptosis | en |
| dc.subject | hsc | en |
| dc.subject | hematopoietic | en |
| dc.title | 7.343 The Radical Consequences of Respiration: Reactive Oxygen Species in Aging and Disease, Fall 2007 | en |
| dc.title.alternative | The Radical Consequences of Respiration: Reactive Oxygen Species in Aging and Disease | en |
| dc.audience.educationlevel | Undergraduate | |
| dc.subject.cip | 260401 | en |
| dc.subject.cip | Cell/Cellular Biology and Histology | en |
| dc.subject.cip | 260202 | en |
| dc.subject.cip | Biochemistry | en |
| dc.date.updated | 2023-03-13T13:41:41Z | |
