Browsing by Author "Zaborenko, Nikolay"
Now showing items 1-3 of 3
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Continuous-flow study and scale-up of conventionally difficult chemical processes
Zaborenko, Nikolay (Massachusetts Institute of Technology, 2010)Microfluidic systems provide valuable tools for exploring, studying, and optimizing organic syntheses. The small scales and fast transport rates allow for faster experiments and lower amounts of chemicals to be used, ... -
Development of an Automated Microfluidic Reaction Platform for Multidimensional Screening: Reaction Discovery Employing Bicyclo[3.2.1]octanoid Scaffolds
Goodell, John R.; McMullen, Jonathan P.; Zaborenko, Nikolay; Maloney, Jason R.; Ho, Chuan-Xing; e.a. (American Chemical Society, 2009-08)An automated, silicon-based microreactor system has been developed for rapid, low-volume, multidimensional reaction screening. Use of the microfluidic platform to identify transformations of densely functionalized bicyclo ... -
Mechanistic Investigations of Epoxide Aminolysis in Microreactors at High Temperatures and Pressures
Zaborenko, Nikolay; Bedore, Matthew W.; Jamison, Timothy F.; Jensen, Klavs F. (American Chemical Society, 2011-01)A continuous-flow microreactor is applied for a kinetic study of a model β-amino alcohol formation by epoxide aminolysis. A large number of experiments are performed in a short time with minimal reagent consumption. The ...