Browsing by Author "F. Hernandez, Ledia"
Now showing items 1-3 of 3
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Effects of dopamine depletion on LFP oscillations in striatum are task- and learning-dependent and selectively reversed by l-DOPA
Lemaire, Nune; Ledia, F. Hernandez; Hu, Dan; Kubota, Yasuo; Howe, Mark William; e.a. (National Academy of Sciences (U.S.), 2012-10)A major physiologic sign in Parkinson disease is the occurrence of abnormal oscillations in cortico-basal ganglia circuits, which can be normalized by l-DOPA therapy. Under normal circumstances, oscillatory activity in ... -
Levodopa-Induced Dyskinesia Is Associated with Increased Thyrotropin Releasing Hormone in the Dorsal Striatum of Hemi-Parkinsonian Rats
Cantuti-Castelvetri, Ippolita; Keller-McGandy, Christine E.; Kett, Lauren R.; Landy, Alex; Hollingsworth, Zane R.; e.a. (Public Library of Science, 2010-11)Background Dyskinesias associated with involuntary movements and painful muscle contractions are a common and severe complication of standard levodopa (L-DOPA, L-3,4-dihydroxyphenylalanine) therapy for Parkinson's ... -
Selective Effects of Dopamine Depletion and L-DOPA Therapy on Learning-Related Firing Dynamics of Striatal Neurons
Hernandez, Ledia F.; Kubota, Yasuo; Hu, Dan; Howe, Mark William; Lemaire, Nune; e.a. (Frontiers Research Foundation, 2013-03)Despite evidence that dopamine neurotransmission in the striatum is critical for learning as well as for movement control, little is yet known about how the learning-related dynamics of striatal activity are affected by ...